Science: Cancer Immunotherapy Top Discovery 2013

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New Year's Eve: “Science” selects cancer immunotherapy as a top discovery in 2013

According to the specialist magazine "Science", progress in cancer immunotherapy is the top scientific discovery of 2013. This year, the strategy that has been researched for decades has finally shown its full potential.

Finally, full potential was shown The specialist magazine "Science" recognized the advances in cancer immunotherapy and chose it as the top scientific discovery in 2013. The editors based their decision in a message on the fact that the strategy that has been researched for decades has finally shown its full potential this year. "A new chapter in cancer research and treatment has started."

Tested on a few cancers Cancer immunotherapy does not focus on the tumor, but rather on the immune system. The method aims to induce immune cells to fight cancer. So far, however, it has only been tested on a few types of cancer and has not yet been extensively tested.

Sleep for restoration and repair Among the nine other discoveries that made it onto the annually published list of the “Science” magazine, there is also the discovery that the human brain cleans and repairs itself during sleep. Using experiments in mice, researchers demonstrated that the brain widens channels between neurons during sleep so that more brain fluid can flow through. According to the scientists, this suggests that renovation and repair are among the most important reasons why people sleep.

Mini-organs grown in the laboratory Furthermore, the "Science" publishers announced that the progress made in the mini-organs grown in the laboratory was remarkable this year. Among other things, such small livers, kidneys and brains were created that could one day be used far better for experimental purposes than experimental animals. The breakthrough in researching the countless microbes living in the body was also recognized. The communication from the specialist magazine states that it has become clear how important these mini-creatures are for humans. For example, intestinal bacteria could contribute to severe malnutrition. A person's microbes would have to be more involved in treatment in the future.

Stem cells from human clone embryos 2013 was also the year in which US researchers succeeded for the first time in producing human clone embryos and extracting stem cells from them. For this they used a method that also led to the so-called clone sheep Dolly. However, they expressly did not want to create clone people. The scientists used a caffeinated solution for their controversial process.

New Method Makes Brain Tissues Appear Transparent Also on the list of top discoveries of the year is the “CRISPR” structure. The discovery of the sections of repeating DNA would have used more than a dozen research teams to change the genome of plants, animals and human cells. The structure is now seen as a scalpel for manipulating individual genes. A new technique to visualize brain tissue was also commended. As the "Science" publisher said, the method of making the tissue appear transparent so that brain cells can be clearly seen "has changed the way researchers look at this complex organ."

New ingredient against childhood disease selected A new ingredient that effectively combats childhood disease and new material for solar cells, which makes it easier and cheaper to manufacture, has also been included in the list. In addition, a discovery from astronomy made it onto the list. In 2013, scientists demonstrated for the first time the assumption that had existed for decades that cosmic radiation can arise from the dust of exploding stars. Last year, the publishers of Science chose the probable discovery of the Higgs particle as the scientific breakthrough of the year. (ad)

Image: Tim Reckmann /

Author and source information

Video: Elizabeth M. Jaffee,., Welcome at 2019 CRI Immunotherapy Patient Summit in Baltimore


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