Resistant bacteria spread

How long will antibiotics be effective against bacterial diseases? Researchers have discovered dangerous enterobacteria that are resistant to almost all antibiotic agents.

(08/12/2010) Scientists from Cardiff University, the Health Protection Agency and other international researchers are currently warning of bacteria that can form the enzyme NDM-1. According to the scientists, the bacteria seem to be spreading the bacterial strain in India and Pakistan. Tourism expects that the resistant bacteria have already reached Europe.

The scientists found that the enterobacteria live in the human gut. The shocking thing is that the bacteria have become resistant to almost all antibiotics. Even reserve antibiotics of carbapenems seem to be unable to do anything against the bacterial strain. Reserve antibiotics are antibiotics that are then used to prevent the development of antibiotic resistance. Reserve antibiotics are used, for example, for so-called hospital germs (e.g. MRSA).

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However, only a few cases of illness have been reported in Pakistan, India and the UK. However, the scientists assume that these resistant bacteria can spread very quickly and could increasingly pose a serious risk to human health.

Englishmen who underwent cosmetic surgery in India for cost reasons have already been infected with these bacteria. According to the BBC, 50 Britons have already contracted the bacteria. It can be assumed that even more people will infiltrate the bacterial strains into Europe, as the so-called medical tourism will continue to grow. This also increases the risk of the resistant bacteria spreading.

But will we make the bacteria resistant to antibiotics? The secret of the resistant bacteria is the enzyme "NDM-1". This enzyme has already been found in many enterobacteria in India and Pakistan. It is easily transferred between bacteria in plasmids. Since the enzyme with the plasmids can easily be exchanged between bacteria, there is a fear that other, further bacteria can no longer be treated effectively.

Researchers are now concerned that NDM-1 could spread to other strains of bacteria that are also resistant to many antibiotic drugs. When the associations are complete, serious infections could spread quickly from person to person. Treatment with an antibiotic is then hardly possible. (sb)

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Video: Basic Mechanisms of Antibiotic Resistance and Gene Spread by Marilyn Roberts, PhD

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